Inflammatory breast cancer (IBC) is the most lethal form of locally advanced breast cancer.We have found that WISP3 is lost in 80% of human IBC tumors and that it has growth- and angiogenesis-inhibitory functions in breast cancer in vitro and in vivo.WISP3 is a cysteine-rich, putatively secreted protein that belongs to the CCN family.It contains a
Applied research is crucial in pushing the boundaries and finding a solution to the age-old problem of dog-mediated rabies.Although oral vaccination of dogs is considered to have great potential in mass dog vaccination campaigns and could have far-reaching benefits, it is perhaps the most ignored of all available tools in efforts to eliminate dog-m
Adoption of proper Islamic law basis towards the concept of one who deserves to be killed and determining criminal sanctions in the case of crimes against one who allegedly deserves to be killed is significant both for the purpose of observing important principles of lawmaking and providing public order and security.Recent approach of criminal poli
Background: Palisaded neutrophilic granulomatous dermatitis is a rare inflammatory dermatosis with possible underlying systemic conditions including rheumatoid arthritis, autoimmune connective tissue disease, and malignancies.Case Summary: We report a case of an 84-year-old man presenting with a 3-week eruption of asymptomatic annular plaques on hi
Background: Penetrating chest trauma can have lethal consequences.Anterior chest wall penetrating injury can cause fatal lacerations over the chest wall, lungs, pericardium, and the heart.There are few reports on these kinds of injuries and operative management.Purpose: To describe a case of penetrating chest trauma with right atrium ruptured, afte